Piao et al generated midbrain dopamine neurons from human embryonic stem cells and manufactured large-scale cryopreserved dopamine progenitors for clinical use. There were no adverse effects attributable to the grafted cells, no obvious distribution outside the brain, and no cell overgrowth or tumor formation, […]
CAMBRIDGE, Mass., Jan. 7, 2021 /PRNewswire/ — BlueRock Therapeutics, a preclinical stage biopharmaceutical company and wholly-owned subsidiary of Bayer AG, in collaboration with Memorial Sloan Kettering Cancer Center (MSK), announced today that the U.S. Food and Drug Administration (FDA) has cleared their Investigational New Drug (IND) application to proceed with a Phase 1 (Ph1) study in patients with advanced Parkinson’s […]
Irion presents a summary of Parkinson’s disease and cell therapeutic approaches. Read more.
Piao et al illustrate that pluripotent stem cells can be used to derive glial cells (oligodendrocytes) which show significant response benefit in pre-clinical models of radiation brain injury. Read more.
